《Novel Biodegradable Laminarin Microparticles for Biomedical Applications》 was written by Castanheira, Edgar J.; Correia, Tiago R.; Rodrigues, Joao M. M.; Mano, Joao F.. Recommanded Product: 3-Bromopropan-1-ol And the article was included in Bulletin of the Chemical Society of Japan in 2020. The article conveys some information:
Fabrication of biocompatible polymeric carriers for sustained/controlled drug-delivery have been extensively explored over the years. Furthermore, systems based on polymers from natural origins exceed conventional polymers in biocompatibility, biodegradability and cost efficiency. Polysaccharides are one of the most common biopolymers found in nature and they can achieve a high degree of complexity and fine biol. properties. Herein, is proposed a biodegradable and biocompatible microcarrier synthesized from laminarin, a low Mw marine polysaccharide based on glucose units with great biol. activity, such as immune modulation and antimicrobial properties. Within this work, controlled size microparticles were obtained from novel modifications of laminarin. Microparticles showed 40% release of fluorescein isothiocyanate-dextran (70 kDa) after 24 h and full degradability after 11 days, when in physiol. conditions. When incubated with human adipose stem and L929 cell lines (up to a microparticle concentration of 100 μg/mL) no cytotoxicity was perceived, and neither membrane or nucleus disturbance. Thus, microparticles synthesized from laminarin, proved to be a cost efficient, biocompatible and biodegradable system. After reading the article, we found that the author used 3-Bromopropan-1-ol(cas: 627-18-9Recommanded Product: 3-Bromopropan-1-ol)
3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Recommanded Product: 3-Bromopropan-1-ol
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