Bowser, Brandon H.; Wang, Shu; Kouznetsova, Tatiana B.; Beech, Haley K.; Olsen, Bradley D.; Rubinstein, Michael; Craig, Stephen L. published the artcile< Single-Event Spectroscopy and Unravelling Kinetics of Covalent Domains Based on Cyclobutane Mechanophores>, COA of Formula: C4H8O, the main research area is spectroscopy unravelling kinetics covalent cyclobutane mechanophore.
Mechanochem. reactions that lead to an increase in polymer contour length have the potential to serve as covalent synthetic mimics of the mech. unfolding of noncovalent “”stored length”” domains in structural proteins. Here we report the force-dependent kinetics of stored length release in a family of covalent domain polymers based on cis-1,2-substituted cyclobutane mechanophores. The stored length is determined by the size (n) of a fused ring in an [n.2.0] bicyclic architecture, and it can be made sufficiently large (>3 nm per event) that individual unravelling events are resolved in both constant-velocity and constant-force single-mol. force spectroscopy (SMFS) experiments Replacing a methylene in the pulling attachment with a Ph group drops the force necessary to achieve rate constants of 1 s-1 from ca. 1970 pN (dialkyl handles) to 630 pN (diaryl handles), and the substituent effect is attributed to a combination of electronic stabilization and mech. leverage effects. In contrast, the kinetics are negligibly perturbed by changes in the amount of stored length. The independent control of unravelling force and extension holds promise as a probe of mol. behavior in polymer networks and for optimizing the behaviors of materials made from covalent domain polymers.
Journal of the American Chemical Society published new progress about Conformers. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, COA of Formula: C4H8O.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts