Badaoui, Antoine published the artcile< Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product>, Name: (E)-5-(4-Hydroxystyryl)benzene-1,3-diol, the main research area is resveratrol Scutellaria root extract cosmetic product allergic contact dermatitis; Scutellaria baicalensis; CAS no 94279-99-9; CAS number 501-36-0; allergic contact dermatitis; case report; cosmetics; eczema; patch test; resveratrol.
Authors report the second case of allergic contact dermatitis caused by resveratrol (CAS number 501-36-0), and Scutellaria baicalensis root extract (CAS no 94279-99-9), both antioxidants, contained in the same cosmetic. A 37-yr-old woman with no past medical history, reported a papular and vesicular eruption of the face and neck, with itchy sensations, 48 h after the application of a new facial cream: Resveratrol BE cream (Skinceuticals). Patch tests were performed with the European baseline and cosmetic series (Chemotechnique Diagnostics), and with the Resveratrol BE cream ‘as is’. Patch test chambers used were IQ ultra (Chemotechnique Diagnostics), fixed with Hypafix (BSN Medical) for 48 h. Patch tests with resveratrol 1% aqueous and S. baicalensis root extract 0.5% aqueous were subsequently performed in four control healthy volunteers and were neg. until D7. Both resveratrol 1% aqueous and S. baicalensis 0.5% aqueous have been tested in healthy patients and showed no pos. reaction, confirming the absence of irritation when tested at these concentrations This case highlights this importance of patch testing all the cosmetics in question brought by the patient, and in case of a pos. reaction, to perform an addnl. patch test with the resp. ingredients, in order to identify new emerging allergens.
Contact Dermatitis published new progress about Allergic contact dermatitis. 501-36-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H12O3, Name: (E)-5-(4-Hydroxystyryl)benzene-1,3-diol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts