Yuan, Yiqiong; Li, Chuan; Zheng, Qianwen; Wu, Jixiang; Zhu, Kexue; Shen, Xuanri; Cao, Jun published the artcile< Effect of simulated gastrointestinal digestion in vitro on the antioxidant activity, molecular weight and microstructure of polysaccharides from a tropical sea cucumber (Holothuria leucospilota)>, Related Products of 3458-28-4, the main research area is Holothuria simulated gastrointestinal digestion polysaccharide antioxidant microstructure.
The physicochem. properties of Holothuria leucospilota polysaccharides (HLP) were measured, and the changes of mol. weight (Mw), antioxidant activity and microstructure in vitro were studied. The Mw of HLP was approx. 52.80 kDa, and the monosaccharide composition was primarily fucose, rhamnose and glucuronic acid. HLP showed good antioxidant activity at high concentration (≥2 mg/mL), and the DPPH (1,1-Diphenyl-2-picryl-hydrazil) free radical scavenging rate reached approx. 84%. It was observed that saliva did not have an effect on the Mw and antioxidant capability of HLP. Gastric and intestinal digestion significantly reduced the Mw of HLP (from 52.80 kDa to 14.67 kDa and 12.01 kDa) and maintained high antioxidant activity. In addition, the structure and surface morphol. were markedly altered. After simulated gastric digestion, the HLP changed from a smooth, irregular, and angular structure to a layered honeycomb with a large volume This result demonstrated that the decrease of Mw after gastric digestion was caused by the destruction of aggregates. Due to the decomposition of glycosidic bonds after digestion in intestine, HLP showed loose, small and blocky structures. Thus, HLP had antioxidant activity, and this activity was improved after gastric and intestinal digestion.
Food Hydrocolloids published new progress about Digestive juice. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Related Products of 3458-28-4.
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