《Simultaneous estimation of ambroxol hydrochloride and cetirizine hydrochloride in combined solid tablet formulations by HPTLC- densitometric method》 was published in Asian Journal of Biochemical and Pharmaceutical Research in 2019. These research results belong to Wadher, Shailesh J.; Supekar, Bhagwan B.; Shivpuje, Shivraj S.. Computed Properties of C13H19Br2ClN2O The article mentions the following:
The new simple, precise, rapid, selective, high performance thin layer chromatog. method has been developed for simultaneous estimation of ambroxol hydrochloride and cetirizine hydrochloride in its combined solid dosage form. The HPTLC method was performed on precoated silica gel G60 F254 plates with Et acetate: methanol: formic acid (7.5: 0.5: 1.0 volume/volume/v) as mobile phase. The plates were developed in 6.00× 0.45mm at room temperature The developed plates were scanned and quantified at their absorption at 222 nm for AMB and CET. The drugs were satisfactorily resolved with Rf = 0.27± 0.01 for CET and 0.43± 0.03 for AMB. Calibration plot was linear between 600-3600 ng/ spot for AMB and 50-300 ng/ spot for CET. This HPTLC method is sensitive, economical, less time consuming than other chromatog. procedures. It can become important tool for anal. of combined solid dosage from.trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride(cas: 23828-92-4Computed Properties of C13H19Br2ClN2O) was used in this study.
trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride(cas: 23828-92-4) enhances pulmonary surfactant production and stimulates ciliary activity.Computed Properties of C13H19Br2ClN2O It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breathe.
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