Takahashi, Kaito published an article in 2022. The article was titled 《Theoretical analysis on reactions between syn-methyl Criegee intermediate and amino alcohols》, and you may find the article in Journal of the Chinese Chemical Society (Weinheim, Germany).SDS of cas: 13325-10-5 The information in the text is summarized as follows:
Due to their strong zwitterionic character, Criegee intermediates can interact strongly with hydrogen bonding mols. in the atm., such as water vapor, alcs., acids, amines, and thiols. To gain a phys. understanding of the reactivity of Criegee intermediates toward these mols., we theor. studied the reaction of syn-CH3CHOO with linear n-amino alc. and branched amino alcs. that contain three carbon atoms. We found that the interaction contribution is the determining factor for the increase in reactivity when we elongate the alkyl chain length and when we place a Me group in the amino group. This finding was rationalized by evaluating the electron-donating ability of the amino alc. Consistent with the increase in reactivity for NH(CH3)C2H4OH and NH2C4H8OH compared to NH2C2H4OH, we found that these two amino alcs. have vertical ionization energies ∼0.5 eV smaller than NH2C2H4OH. In the experiment, the researchers used 4-Aminobutan-1-ol(cas: 13325-10-5SDS of cas: 13325-10-5)
4-Aminobutan-1-ol(cas: 13325-10-5) is used in the synthesis of NSAIDs with anti-inflammatory properties. Also used in the synthesis of polyamine transport ligands with specificity against human cancers allowing easy access to specific cancer cells.SDS of cas: 13325-10-5
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts