《Protecting-group-free synthesis of hydroxyesters from amino alcohols》 was written by Reynard, Guillaume; Joseph-Valcin, Eve-Marline; Lebel, Helene. Application In Synthesis of 4-Aminobutan-1-ol And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:
The synthesis of hydroxyesters such as RCOOCH2(CH)nOH [R = MeC≡C, 2-furyl, Ph, etc.; n = 1,2,3,4,7] from carboxylic acids RCOOH and unprotected amino alcs. H2NCH2(CH)nOH in both continuous flow and batch processes was reported. The formation of a transient diazonium species with a dinitrite reagent was key in this transformation. The reaction conditions were compatible with a variety of functional groups. In the experimental materials used by the author, we found 4-Aminobutan-1-ol(cas: 13325-10-5Application In Synthesis of 4-Aminobutan-1-ol)
4-Aminobutan-1-ol(cas: 13325-10-5) is used in the synthesis of NSAIDs with anti-inflammatory properties. Also used in the synthesis of polyamine transport ligands with specificity against human cancers allowing easy access to specific cancer cells.Application In Synthesis of 4-Aminobutan-1-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts