Oloo, Williamson N’s team published research in Inorganic Chemistry in 2022-01-10 | 76-84-6

Inorganic Chemistry published new progress about Alkenes Role: BUU (Biological Use, Unclassified), SPN (Synthetic Preparation), BIOL (Biological Study), USES (Uses), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Computed Properties of 76-84-6.

Oloo, Williamson N.; Szavuly, Miklos; Kaizer, Jozsef; Que, Lawrence Jr. published the artcile< Nonheme diiron oxygenase mimic that generates a diferric-peroxo intermediate capable of catalytic olefin epoxidation and alkane hydroxylation including cyclohexane>, Computed Properties of 76-84-6, the main research area is nonheme diiron oxygenase mimic intermediate olefin epoxidation alkane hydroxylation.

Herein are described substrate oxidations with H2O2 catalyzed by [FeII(IndH)(CH3CN)3](ClO4)2 [IndH = 1,3-bis(2′-pyridylimino)isoindoline], involving a spectroscopically characterized (μ-oxo)(μ-1,2-peroxo)diiron(III) intermediate (2) that is capable of olefin epoxidation and alkane hydroxylation including cyclohexane. Species 2 also converts ketones to lactones with a decay rate dependent on [ketone], suggesting direct nucleophilic attack of the substrate carbonyl group by the peroxo species. In contrast, peroxo decay is unaffected by the addition of olefins or alkanes, but the label from H218O is incorporated into the epoxide and alc. products, implicating a high-valent iron-oxo oxidant that derives from O-O bond cleavage of the peroxo intermediate. These results demonstrate an ambiphilic diferric-peroxo intermediate that mimics the range of oxidative reactivities associated with O2-activating nonheme diiron enzymes.

Inorganic Chemistry published new progress about Alkenes Role: BUU (Biological Use, Unclassified), SPN (Synthetic Preparation), BIOL (Biological Study), USES (Uses), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Computed Properties of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts