Nakajima, Isami; Shimizu, Minori; Okuda, Yuta; Akiyama, Ryo; Tadano, Ryu; Nagaoka, Masahiro; Uemura, Naohiro; Yoshida, Yasushi; Mino, Takashi; Shinozaki, Hiraku; Yamamoto, Tetsuya published the artcile< Synthesis and Catalysis of NHC Coordinated Cyclometalated Palladium(II) Complexes with Bridging Hydroxide Ligands>, Category: alcohols-buliding-blocks, the main research area is hydroxide palladium NHC addition catalyst boronic ester aldehyde ketone; crystal structure mol dipalladium hydroxide bridged heterocyclic carbene complex; palladium hydroxide bridged NHC cyclometalated dimer complex preparation.
1,2-Addition reactions using organoboron compounds are one of the useful syntheses of various functionalized alcs., but they generally require a large quantity of bases. In this study, we attempted to solve this problem by synthesizing unsym. 1,3-diarylimidazoline-type N-heterocyclic carbene (NHC)-coordinated CĈ* cyclometalated palladium(II) complexes with bridging hydroxide ligands (CYPOHs) in two steps and one pot from the corresponding Cl bridged dimer and using them as catalysts. 2,6-Di(pentan-3-yl)aniline (IPent)-based NHC coordinated PhS-IPent-CYPOH acted as a highly efficient catalyst for the 1,2-addition of (hetero)arylboronates to a large number of aldehydes and ketones, including unactivated ketones, under base-free conditions.
Advanced Synthesis & Catalysis published new progress about 1,2-Addition reaction. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Category: alcohols-buliding-blocks.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts