《Imaging mitochondria and plasma membrane in live cells using solvatochromic styrylpyridines》 was published in Journal of Photochemistry and Photobiology, B: Biology in 2020. These research results belong to Mukherjee, Tarushyam; Aravintha Siva, M.; Bajaj, Komal; Soppina, Virupakshi; Kanvah, Sriram. Reference of 3-Bromopropan-1-ol The article mentions the following:
In this study, we have synthesized four fluorescent styrene derivatives, a neutral styrylpridine, three cationic styrylpyridinium probes with and without cholesterol tether, and investigated their absorption, emission, and cellular imaging properties. The fluorophores show solvatochromic emission attributed to intramol. charge transfer from donor to acceptor with an emission range of 500-600 nm. The fluorescent cholesterol conjugate labels plasma membrane effectively while the fluorophores devoid of the cholesterol tether label mitochondria. Cholesterol conjugate also shows strong interaction with liposome membrane. Furthermore, the fluorophores alsotrack the mitochondria in live cells with high specificity. Cell viability assay showed overall non-toxic nature of the probes even at higher fluorophore concentrations Through sidearm modifications, keeping the fluorescent core intact, we successfully targeted specific subcellular compartments of neuronal (N2a) and non-neuronal (HeLa) mammalian cell lines. This strategy of using a single mol. scaffold with subtle substitutions could be ideal in generating a variety of fluorophores targeting other subcellular compartments. After reading the article, we found that the author used 3-Bromopropan-1-ol(cas: 627-18-9Reference of 3-Bromopropan-1-ol)
3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Reference of 3-Bromopropan-1-ol
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