《New eugenol derivatives with enhanced insecticidal activity》 was written by Fernandes, Maria Jose G.; Pereira, Renato B.; Pereira, David M.; Fortes, A. Gil; Castanheira, Elisabete M. S.; Goncalves, M. Sameiro T.. SDS of cas: 627-18-9 And the article was included in International Journal of Molecular Sciences in 2020. The article conveys some information:
Eugenol, the generic name of 4-allyl-2-methoxyphenol, is the major component of clove essential oil, and has demonstrated relevant biol. potential with well-known antimicrobial and antioxidant actions. New O-alkylated eugenol derivatives, bearing a Pr chain with terminals like hydrogen, hydroxyl, ester, chlorine, and carboxylic acid, were synthesized in the present work. These compounds were later subjected to epoxidation conditions to give the corresponding oxiranes. All derivatives were evaluated against their effect upon the viability of insect cell line Sf9 (Spodoptera frugiperda), demonstrating that structural changes elicit marked effects in terms of potency. In addition, the most promising mols. were evaluated for their impact in cell morphol., caspase-like activity, and potential toxicity towards human cells. Some mols. stood out in terms of toxicity towards insect cells, with morphol. assessment of treated cells showing chromatin condensation and fragmentation, which are compatible with the occurrence of programmed cell death, later confirmed by evaluation of caspase-like activity. These findings point out the potential use of eugenol derivatives as semisynthetic insecticides from plant natural products.3-Bromopropan-1-ol(cas: 627-18-9SDS of cas: 627-18-9) was used in this study.
3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.SDS of cas: 627-18-9
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