Zhao, Peng; El-kott, Attalla; Ahmed, Ahmed Ezzat; Khames, Ahmed; Zein, Mohamed Abdellatif published the artcile< Green synthesis of gold nanoparticles (Au NPs) using Tribulus terrestris extract: Investigation of its catalytic activity in the oxidation of sulfides to sulfoxides and study of its anti-acute leukemia activity>, Computed Properties of 699-12-7, the main research area is green preparation gold nanoparticle; XRD particle size distribution gold nanoparticle; sulfide oxidation gold nanoparticle catalyst; sulfoxide preparation catalyst gold nanoparticle; antiacute leukemia activity gold nanoparticle; antioxidant activity gold nanoparticle; cytotoxicity gold nanoparticle.
With regards to applied, facile, green chem. research, a bio-inspired approach is being reported for the synthesis of Au NPs by using Tribulus terrestris extract The innate oxygenated phytochems. facilitated the green reduction of Au3+ ions to corresponding NPs and also stabilized them by encapsulating them. This modification prevented the as-synthesized Au NPs towards agglomeration and tiny NPs were obtained in uniformly spherical in shape and at 10-15 nm dimension. Physicochem. characteristics of the green synthesized Au NPs were evaluated by advanced physicochem. techniques like UV-visible and FTIR spectroscopy, SEM, TEM, EDX and XRD study. Catalytic performance of the biomol. functionalized Au NPs was studied in the controlled and selective oxidation of sulfides to sulfoxides using hydrogen peroxide as green oxidant at room temperature Aromatic, aliphatic and heterocyclic sulfides were oxidized to their corresponding sulfoxides with high yields without formation of over oxidized sulfones. The catalyst was easily recovered and recycled for 8 successive times without noticeable decrease in catalytic activity. In addition, the biosynthesized Au NPs indicated suitable antioxidant and anti-acute leukemia properties against THP-1 cell line. Tribulus terrestris extract and the green synthesized Au NPs exhibited a maximum DPPH scavenging activity of 78% and 29.37%, resp. Again, in the anticancer studies over THP-1 cell line following MTT assay, the Au NP exhibited gradual reduced % cell viability with increase in its concentration At an Au NPs concentration of 2000μg/mL, the % toxicity became maximum suggesting efficient inhibition of cancer invasion. Based on the above results, Au NPs-Tribulus could be administered as a potential anti-leukemia drug for the treatment of acute leukemia following the clin. trial studies in humans.
Inorganic Chemistry Communications published new progress about Cytotoxicity. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Computed Properties of 699-12-7.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts