Yun, Xue-Jing; Zhu, Jing-Wei; Jin, Yan; Deng, Wei; Yao, Zi-Jian published the artcile< Half-Sandwich Ruthenium Complexes for One-Pot Synthesis of Quinolines and Tetrahydroquinolines: Diverse Catalytic Activity in the Coupled Cyclization and Hydrogenation Process>, Application In Synthesis of 5344-90-1, the main research area is ruthenium half sandwich cyclometalated complex preparation hydrogenation catalyst; amine ketone hydrogenation catalyst ruthenium half sandwich cyclometalated complex.
Four types of half-sandwich ruthenium complexes with an N,O-coordinate mode based on hydroxyindanone-imine ligands have been prepared in good yields. These stable ruthenium complexes exhibited high activity in the catalytic synthesis of quinolines from the reactions of amino alcs. with different types of ketones or secondary alcs. under very mild conditions. Moreover, the methodol. for the direct one-pot synthesis of tetrahydroquinoline derivatives from amino alcs. and ketones has been also developed on the basis of the continuous catalytic activity of this ruthenium catalyst in the selective hydrogenation of the obtained quinoline derivatives with a low catalyst loading. The corresponding products, quinolines and tetrahydroquinoline derivatives, were afforded in good to excellent yields. The efficient and diverse catalytic activity of these ruthenium complexes suggested their potential large-scale application. All of the ruthenium complexes were characterized by various spectroscopies to confirm their structures. Half-sandwich ruthenium complexes based on hydroxyindanone-imine ligands exhibited high activity in the catalytic synthesis of quinoline derivatives starting from amino alcs. and ketones as well as secondary alcs. under very mild conditions. One-pot synthesis of tetrahydroquinoline has been also developed on the basis of the continuous catalytic activity of these ruthenium catalysts in selective hydrogenation.
Inorganic Chemistry published new progress about Aralkyl amines Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application In Synthesis of 5344-90-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts