Si, Xiaojia; Zhang, Lumin; Wu, Zuozuo; Rudolph, Matthias; Asiri, Abdullah M.; Hashmi, A. Stephen K. published the artcile< Visible Light-Induced α-C(sp3)-H Acetalization of Saturated Heterocycles Catalyzed by a Dimeric Gold Complex>, Related Products of 4064-06-6, the main research area is acetalization heterocycle gold catalyst visible light; cross coupling dehydrogenative ether tetrahydrothiophene pyrrolidine gold catalyst.
Saturated heterocyclic acetals are useful fragments in organic synthesis and other fields. Herein, C(sp3)-H dehydrogenative cross-couplings of ethers, tetrahydrothiophene, and N-Boc-pyrrolidine were achieved under visible light irradiation by using 4-iodoanisole and an in situ-formed gold complex. The broad functional group compatibility and substrate scope indicate that our strategy is a promising way to synthesize acetal analogs. The method was successfully applied in late-stage modifications of bioactive mols. Gram scale syntheses and mechanistic studies are also presented.
Organic Letters published new progress about Acetalization. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Related Products of 4064-06-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts