Shadrick, Melanie; Singh, Yashapal; Demchenko, Alexei V. published the artcile< Stereocontrolled α-Galactosylation under Cooperative Catalysis>, Related Products of 4064-06-6, the main research area is disaccharide preparation stereoselective galactosylation catalyzed; stereoselective galactosylation catalyzed protecting group glycosyl halide glycoside preparation.
A recent discovery of a cooperative catalysis comprising a silver salt and an acid led a dramatic improvement in the way glycosyl halides are glycosylated. Excellent yields have been achieved, but the stereoselectivity achieved with 2-O-benzylated donors was poor. Reported herein is our first attempt to refine the stereoselectivity of the cooperatively catalyzed galactosylation reaction. Careful optimization of the reaction conditions along with studying effects of the remote protecting groups led to excellent stereocontrol of α-galactosylation of a variety of glycosyl acceptors with differentially protected glycosyl donors.
Journal of Organic Chemistry published new progress about Catalysis. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Related Products of 4064-06-6.
Referemce:
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Alcohols – Chemistry LibreTexts