Semeniuchenko, Volodymyr; Sharif, Sepideh; Day, Jonathan; Chandrasoma, Nalin; Pietro, William J.; Manthorpe, Jeffrey; Braje, Wilfried M.; Organ, Michael G. published the artcile< (DiMeIHeptCl)Pd: A Low-Load Catalyst for Solvent-Free (Melt) Amination>, Electric Literature of 5344-90-1, the main research area is halobenzene amine palladium catalyst aryl amination; phenyl amine preparation.
(DiMeIHeptCl)Pd, a hyper-branched N-aryl Pd NHC catalyst, was shown to be efficient at performing amine arylation reactions in solvent-free (“”melt””) conditions. The highly lipophilic environment of the alkyl chains flanking the Pd center served as lubricant to allow the complex to navigate through the paste-like environment of these mixtures The protocol was used on a multi-gram scale to make a variety of aniline derivatives, including substrates containing alc. moieties.
Journal of Organic Chemistry published new progress about Amination. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Electric Literature of 5344-90-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts