Ngai, Courtney; Wu, Hoi-Ting; da Camara, Bryce; Williams, Christopher G.; Mueller, Leonard J.; Julian, Ryan R.; Hooley, Richard J. published the artcile< Moderated Basicity of Endohedral Amine Groups in an Octa-Cationic Self-Assembled Cage>, Recommanded Product: Triphenylmethanol, the main research area is preparation moderated basicity endohedral octa cationic self assembled cage; mol structure moderated basicity endohedral octa cationic self assembled; Coordination Chemistry; Enzyme Models; Molecular Recognition; Self-Assembly; Supramolecular Chemistry.
A self-assembled FeII4L6 cage was synthesized with 12 internal amines in the cavity. The cage forms as the dodeca-ammonium salt, despite the cage carrying an overall 8+ charge at the metal centers, extracting protons from displaced water in the reaction. Despite this, the basicity of the internal amines is lower than their counterparts in free solution The 12 amines have a sliding scale of basicity, with a ≈ 6 pKa unit difference between the first and last protons to be removed. This moderation of side-chain basicity in an active site is a hallmark of enzymic catalysis.
Angewandte Chemie, International Edition published new progress about Directed assembly. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Recommanded Product: Triphenylmethanol.
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