Liu, Xu-Teng; Han, Xue-Yu; Wu, Yue; Sun, Ying-Ying; Gao, Li; Huang, Zhuo; Zhang, Qing-Wei published the artcile< Ni-Catalyzed Asymmetric Hydrophosphination of Unactivated Alkynes>, Category: alcohols-buliding-blocks, the main research area is nickel catalyzed asym regioselective enantioselective hydrophosphination unactivated alkyne; phosphorus stereogenic tertiary phosphine preparation reaction; crystal mol structure alkenyl phosphine borane sulfide ruthenium platinum.
The practical synthesis of P-stereogenic tertiary phosphines, which have wide applications in asym. catalysis, materials, and pharmaceutical chem., represents a significant challenge. A regio- and enantioselective hydrophosphination using cheap and ubiquitous alkynes catalyzed by a nickel complex was designed, in which the toxic and air-sensitive secondary phosphines were prepared in situ from bench-stable secondary phosphine oxides. This methodol. has been demonstrated with unprecedented substrate scope and functional group compatibility to afford electronically and structurally diversified P(III) compounds The products could be easily converted into various precursors of bidentate ligands and organocatalysts, as well as a variety of transition-metal complexes containing both P- and metal-stereogenic centers.
Journal of the American Chemical Society published new progress about Alkynes Role: RCT (Reactant), RACT (Reactant or Reagent) (unactivated). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Category: alcohols-buliding-blocks.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts