Liu, Jiahao; Li, Weikang; Li, Yinwu; Liu, Yan; Ke, Zhuofeng published the artcile< Selective C-alkylation between Alcohols Catalyzed by N-Heterocyclic Carbene Molybdenum>, Reference of 403-41-8, the main research area is primary secondary alc molybdenum complex alkylation chemoselectivity green chem; secondary alc preparation; Alcohols; Alkylation; Borrowing hydrogen; Molybdenum catalysis; N-heterocyclic carbene.
The implementation of a molybdenum complex with an easily accessible bis-N-heterocyclic carbene ligand to catalyze β-alkylation of secondary alcs. via borrowing-hydrogen (BH) strategy using alcs. as alkylating agents was reported. Remarkably high activity, excellent selectivity and broad substrate scope compatibility with advantages of catalyst usage low to 0.5 mol%, a catalytic amount of NaOH as the base and H2O as the byproduct were demonstrated in this green and step-economical protocol. Mechanistic studies indicated a plausible outer-sphere mechanism in which the alc. dehydrogenation is the rate-determining step.
Chemistry – An Asian Journal published new progress about Alkylation catalysts (chemoselective). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Reference of 403-41-8.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts