Laengle, D.; Wesseler, F.; Floetgen, D.; Leek, H.; Plowright, A. T.; Schade, D. published the artcile< Unique photoaffinity probes to study TGFβ signaling and receptor fates>, COA of Formula: C4H8N2O, the main research area is dihydropyridine annulated preparation transforming growth factor beta pharmacophore SAR.
A novel synthetic approach is used to prepare a diverse set of “”first-in-class”” dihydropyridine-based TGFβ receptor degraders bearing photoaffinity labels. These probes serve as valuable tools to study TGFβ receptor fates and dynamics – an important challenge in chem. biol.
Chemical Communications (Cambridge, United Kingdom) published new progress about Dihydropyridines Role: DGN (Diagnostic Use), PAC (Pharmacological Activity), PEP (Physical, Engineering or Chemical Process), PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), THU (Therapeutic Use), BIOL (Biological Study), USES (Uses), PROC (Process), RACT (Reactant or Reagent), PREP (Preparation). 25055-82-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8N2O, COA of Formula: C4H8N2O.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts