Qiao, Lizhen;Sun, Ruiting;Tao, Yuan;Yan, Yang published 《New low viscous hydrophobic deep eutectic solvents for the ultrasound-assisted dispersive liquid-liquid microextraction of endocrine-disrupting phenols in water, milk and beverage》. The research results were published in《Journal of Chromatography A》 in 2022.Safety of 4-(2-Phenylpropan-2-yl)phenol The article conveys some information:
In the present work, several new hydrophobic deep eutectic solvents (HDESs) were prepared with quaternary ammonium salts as hydrogen bond acceptors (HBAs) and salicylate esters as hydrogen bond donors (HBDs). Then, the obtained HDESs were used as extraction solvents to establish an ultrasound-assisted dispersive liquid-liquid microextraction method combined with high-performance liquid chromatog.-UV detection technique for the determination of four endocrine-disrupting phenols (EDPs) compounds One of the obtained HDESs composed of tetrabutylammonium chloride (N4444Cl) and Me salicylate possessed a viscosity of 89.28 mPa·s lower than most reported ionic HDESs (>200 mPa·s), and the low viscous HDES was selected as the optimal extraction solvent. Several key parameters affecting the extraction efficiency were investigated, including the type and volume of HDES, ultrasound time, sample solution pH and salt addition Under the optimized exptl. conditions, the proposed method had good coefficients of determination (R2 > 0.9976) in the linear range of 0.5-400μg·L-1, the limits of quantification and limits of detection resp. were 0.5-2.5μg·L-1 and 0.25-1μg·L-1, and the recoveries were in the range of 81.79-109.82%. Finally, the method was used for the preconcentration and determination of EDPs in different samples, including bottled water, tea beverage and milk.4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) were involved in the experimental procedure.
4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.Safety of 4-(2-Phenylpropan-2-yl)phenol 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.
Reference:
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Alcohols – Chemistry LibreTexts