Jakubczyk, Karolina; Skonieczna-Zydecka, Karolina; Kaldunska, Justyna; Stachowska, Ewa; Gutowska, Izabela; Janda, Katarzyna published the artcile< Effects of resveratrol supplementation in patients with non-alcoholic fatty liver disease-a meta-analysis>, Name: (E)-5-(4-Hydroxystyryl)benzene-1,3-diol, the main research area is meta analysis resveratrol hepatoprotectant nonalcoholic fatty liver disease; Non-alcoholic fatty liver disease (NAFLD); meta-analysis; resveratrol.
Non-alc. fatty liver disease (NAFLD) is regarded as one of the most common liver pathologies in many societies. Resveratrol, as a phenolic compound with powerful antioxidant and anti-inflammatory properties exerting pos. effects on the lipid profile and lipid accumulation and also on insulin resistance, appears to be an effective, natural, and safe complementary treatment option in NAFLD therapy. This meta-anal. was undertaken to evaluate the effects of resveratrol supplementation in NAFLD patients. To this end, scientific databases PubMed/Medline/Embase were searched up to 19 March 2020. We included seven randomized clin. trials (RCTs) with a total of 302 patients with NAFLD. In all the trials included in the anal., resveratrol was administered daily over periods between 56 and 180 days in doses ranging from 500 mg to 3000 mg a day. The results of this meta-anal. reveal that resveratrol supplementation, irresp. of the dose or duration, did not affect the analyzed parameters (p < 0.05). The sole exception was an increase in alanine aminotransferase following the administration of resveratrol (p = 0.041). Currently available evidence is insufficient to confirm the efficacy of resveratrol in the management of NAFLD. Due to the inconsistencies between the existing scientific reports, a number of which found a pos. effect on NAFLD-related parameters; further research in this area is needed. Nutrients published new progress about Anti-inflammatory agents. 501-36-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H12O3, Name: (E)-5-(4-Hydroxystyryl)benzene-1,3-diol.
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