Huang, Xiang-tao; Li, Xi; Xie, Ming-ling; Huang, Zhen; Huang, Yong-xiu; Wu, Gui-xian; Peng, Zhi-rong; Sun, Yan-ni; Ming, Qian-liang; Liu, Yan-xia; Chen, Jie-ping; Xu, Shuang-nian published the artcile< Resveratrol: Review on its discovery, anti-leukemia effects and pharmacokinetics>, SDS of cas: 501-36-0, the main research area is review resveratrol antileukemia agent pharmacokinetics leukemia; Anti-Leukemia; Drug candidate; Resveratrol.
A review. Resveratrol, found in variety of plants, is a natural stilbene structure polyphenol. It has various pharmacol. effects, such as antioxidation, anti-aging, anti-inflammation, anti-cancer, antiobesity, anti-diabetes, cardioprotection, neuroprotection. Recently, anti-leukemia activities of resveratrol has been studied extensively via its effects on a variety of biol. processes involving cell proliferation, apoptosis, autophagy. Current treatments of leukemia mainly rely on intensive chemotherapy or hematopoietic stem cell transplantation, however, these treatments are still with poor survival and high treatment-related mortality. Therefore, it is extremely needed to find relatively non-toxic medicines with minimal side effects but sufficient therapeutic efficacy. Resveratrol is one such potential candidate owing to its reported anti-leukemia effect. In this review, we summarized resveratrol’s discovery, sources and isolation methods, administration methods, effects in different types of leukemia, pharmacokinetics and toxicities, aiming to exploit resveratrol as a potential drug candidate for anti-leukemia.
Chemico-Biological Interactions published new progress about Anti-aging agents. 501-36-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H12O3, SDS of cas: 501-36-0.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts