Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol《Aerobic oxidation of alcohols with air catalyzed by decacarbonyldimanganese》 was published in 2019. The authors were Meng, Shan-Shui;Lin, Li-Rong;Luo, Xiang;Lv, Hao-Jun;Zhao, Jun-Ling;Chan, Albert S. C., and the article was included in《Green Chemistry》. The author mentioned the following in the article:
The oxidation of alcs. to carbonyl compounds using air as the terminal oxidant is highly desirable. As described in previous reports, the abstraction of α-H of the alc. is the most important step, and it typically requires not only a metal catalyst but also complex ligands, co-catalysts and bases. Herein, we report a practical and efficient method for the oxidation of primary alcs., secondary alcs., 1,2-diols, 1,2-amino alcs., and other α-functionalized alcs. using a com. available catalyst, Mn2(CO)10, and no additives. Preliminary mechanistic studies indicated that an alkoxyl radical intermediate existed in our system, and a plausible mechanism consistent with the exptl. results and literature was proposed.rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) were involved in the experimental procedure.
Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.
Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts