Formula: C14H14O2《Iron-catalyzed one-pot synthesis of quinoxalines: transfer hydrogenative condensation of 2-nitroanilines with vicinal diols》 was published in 2021. The authors were Putta, Ramachandra Reddy;Chun, Simin;Lee, Seok Beom;Hong, Junhwa;Oh, Dong-Chan;Hong, Suckchang, and the article was included in《RSC Advances》. The author mentioned the following in the article:
Here, iron-catalyzed one-pot synthesis of quinoxalines via transfer hydrogenative condensation of 2-nitroanilines with vicinal diols was reported. The tricarbonyl (η4-cyclopentadienone) iron complex, which was well known as the Knolker complex, catalyzed the oxidation of alcs. and the reduction of nitroarenes, and the corresponding carbonyl and 1,2-diaminobenzene intermediates were generated in situ. Trimethylamine N-oxide was used to activate the iron complex. Various unsym. and sym. vicinal diols were applied for transfer hydrogenation, resulting in quinoxaline derivatives in 49-98% yields. A plausible mechanism was proposed based on a series of control experiments The major advantages of this protocol were that no external redox reagents or addnl. base was needed and that water is liberated as the sole byproduct. To complete the study, the researchers used rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .
Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Formula: C14H14O2) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.
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