Today I want to share an article with you. The article is 《Acridine-Based SNS-Ruthenium Pincer Complex-Catalyzed Borrowing Hydrogen-Mediated C-C Alkylation Reaction: Application to the Guerbet Reaction》,you can find this article in 《Synlett》. The following contents are mentioned:
SNS-based ruthenium pincer catalysts were applied in a Guerbet condensation reaction of primary alcs. to give β-alkylated dimeric alcs. I [R = Et, n-Bu, n-hexyl, etc.; R1 = Me, n-Bu, n-hexyl, etc.] in good yields. The ability of these complexes to convert ethanol into butanol was also investigated. The work was then extended toward the C-alkylation of secondary alcs. with primary alcs. to give α-alkylated ketones II [R2 = H, 4-OMe, 4-Me, etc. R3 = Ph, 4-ClC6H4, 4-FC6H4, etc.]. Several control experiments showed the involvement of borrowing hydrogen in the protocol. To complete the study, the researchers used 2-Hexyl-1-decanol (cas: 2425-77-6) .
2-Hexyl-1-decanol(cas: 2425-77-6) is a fatty acid that is found in the essential oils of plants and has been shown to have fungicidal properties.Electric Literature of C16H34O It has also been shown to inhibit the growth of Candida glabrata when used as a cationic surfactant.
Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts