Month: September 2022

Today I want to share an article with you. The article is 《Occurrence and tissue distribution of alkylphenols (APs) in selected waterbirds from the Southern Baltic》,you can find this article in 《Chemosphere》. The following contents are mentioned:

The aim of the present study was to determine the concentrations of nonylphenols (NPs) and 4-t-octylphenol (4tOP) in the muscles, liver, and kidneys of selected waterbird species. Three species with different feeding habits were selected, i.e., greater scaup (Aythya marila), great crested grebe (Podiceps cristatus), and great cormorant (Phalacrocorax carbo) to investigate the potential effects of diet on the level of contaminants tested. The determination and quantification of analytes were performed using gas chromatog. with mass spectrometric detection (GC-MS). The highest NP concentrations were noted in the kidneys of greater scaups and great crested grebes (208.3 and 160.8 μg kg-1 ww, resp.), which were six to fourteen-fold higher than those in the muscles (15.0 and 25.6 μg kg-1 ww, resp.) and livers (22.9 and 13.8 μg kg-1 ww, resp.) of these species. In greater scaups, the mean concentration of NPs in the livers was lower than in the muscles, while in great crested grebes, it was the opposite and higher concentrations were noted in the muscles. The mean concentrations of NPs in the muscles and livers of great cormorants were at similarly low levels (12.5 and 9.7 μg kg-1 ww, resp.). The concentrations of 4tOP in all samples were low, ranging from <LOQ to 0.29 μg kg-1 ww. The results of our study indicated that sex and diet did not affect the NP tissue concentrations in different waterbird species, but the phenol. period (migration vs breeding) might influence the contamination levels in the kidneys. The experimental procedure involved many compounds, such as 4-tert-Octylphenol (cas: 140-66-9) .

4-tert-Octylphenol(cas: 140-66-9) has been used as a reference standard for the determination of the analyte in water samples using ultra-high-performance liquid chromatography/tandem mass spectrometry (UHPLC/MS/MS).Name: 4-tert-Octylphenol

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Related Products of 80-46-6In 2015, Di Nicola, Giovanni;Pierantozzi, Mariano published 《Surface tension of alcohols: A scaled equation and an artificial neural network》. 《Fluid Phase Equilibria》published the findings. The article contains the following contents:

This work presents a new formula to calculate the surface tension of alcs.As a first step, an anal. of the data available on the surface tension of alcs. was made. A total of 2121 data were collected for n-alcs., aromatic alcs., cycloaliphatic alcs., 2-alkanols and Me alkanols. The data were then regressed with the most reliable semi-empirical correlation methods in the literature based on the corresponding states theory. The scaled equation proposed is very simple and gives noticeable improvement with respect to existing equations.The same phys. parameters considered in the scaled equation were also adopted as input parameters in a multi-layer perceptron neural network, to predict the surface tension of alcs. The multilayer perceptron proposed has one hidden layer with 29 neurons, determined according to the constructive approach. The model developed was trained, validated and tested for the set of data collected, showing that the accuracy of the neural network model is very good. And 4-tert-Amylphenol (cas: 80-46-6) was used in the research process.

4-tert-acylphenol (cas:80-46-6) contains hydroxyl group. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble.Related Products of 80-46-6

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jana, Barun published 《Synthesis, characterization and crystal structure determination of aluminum hydride complexes of N,N’-Di(isopropyl)ethylenediamine ligand》. The research results were published in《Journal of Molecular Structure》 in 2021.Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol The article conveys some information:

Reaction of alane-amine adduct, AlH₃·NMe₂Et, with N,N’-di(isopropyl)ethylenediamine was conducted for the preparation of amide ligated aluminum hydride complexes via dehydrocoupling pathway. Depending on the proportion of the reagents (1:1 and 3:2) two different products (1) and (2) were isolated. Compounds 1 and 2 were characterized using different spectroscopic techniques along with the determination of solid-state mol. structure via single crystal x-ray diffraction studies. In the crystal lattice of complex 2, mols. are connected via weak Al-H…H-C hydrogen bonding supramol. interactions to form polymeric arrangements of the mol. Further, a reaction of 2 with two equivalent of 1,2-diphenylethylene-glycol generated complex 3 that was isolated in trace quantities. Mol. structure of 3 was also determined using single crystal x-ray diffraction study. And rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) was used in the research process.

Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Category: alcohols-buliding-blocksIn 2011, Pan, Xingang;Jia, Liangbin;Liu, Xuejian;Ma, Haikuo;Yang, Wenqian;Schwarz, Jacob B. published 《A general asymmetric synthesis of phenylglycinols》. 《Tetrahedron: Asymmetry》published the findings. The article contains the following contents:

Hydride reduction and deprotection of siloxymethyl sulfinimines, e.g., I, reliably furnished chiral phenylglycinols, e.g., II or III, in high overall yield and enantiomeric purity. The experimental procedure involved many compounds, such as (S)-2-Amino-2-(4-fluorophenyl)ethanol (cas: 224434-01-9) .

(S) – 2-amino-2 – (4-fluorophenyl) ethanol (cas: 224434-01-9) has the characteristics of alcohol. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Category: alcohols-buliding-blocks

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hamow, Kamiran Aron;Ambrozy, Zsuzsanna;Puskas, Katalin;Majlath, Imre;Cseplo, Monika;Matyus, Reka;Posta, Katalin;Lukacs, Peter;Sagi, Laszlo published 《Emission of novel volatile biomarkers for wheat powdery mildew》 in 2021. The article was appeared in 《Science of the Total Environment》. They have made some progress in their research.Recommanded Product: 3,7-Dimethyloctan-3-ol The article mentions the following:

Natural ecosystems including host-pathogen interactions produce a plethora of biogenic volatile organic compounds (BVOCs). Infections by phytopathogens change the volatile profile substantially and dynamically over a crop field or even on a larger scale. Despite their worldwide importance in agriculture little is known about the BVOC emissions of cereal crops, such as wheat, and their pathogens. The wheat-powdery mildew interaction is especially relevant, because powdery mildew is widespread on a global scale and is caused by an obligatory biotrophic pathogen (Blumeria graminis f.sp. tritici, Bgt). Since the BVOCs in this important fungus have still not been identified, the most frequent local natural pathotypes were studied by artificial inoculation and dynamic headspace collection followed by GC-MS anal. in three consecutive years. Of the 48 BVOCs identified in a total of 120 samples, six compounds (1,3-octadiene, 1,3-cis,5-cis-octatriene, 1-heptanol, (5Z)-octa-1,5-dien-3-ol, 1-octen-3-ol and 3-octanone) were detected only in Bgt-inoculated plants, and were hence quantitated. The latter three BVOCs were the most abundant in symptomatic plants with a characteristic distribution pattern. Addnl. wheat genotypes, different host plant development stages, and early and full disease progression in the presence of other pathogen mixes were also tested for the specificity of the proposed biomarkers. The three major biomarkers, namely (5Z)-octa-1,5-dien-3-ol, 1-octen-3-ol and 3-octanone were robustly applicable for differentiating the headspaces of healthy and mildew-infected plants even at early stages when disease symptoms are barely visible. These novel powdery mildew-related biomarkers are promising candidates for chemotyping and environmental monitoring in the field.3,7-Dimethyloctan-3-ol (cas: 78-69-3) were involved in the experimental procedure.

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Recommanded Product: 3,7-Dimethyloctan-3-ol Metabolite observed in cancer metabolism. It has a role as a human metabolite.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Safety of 4-tert-Amylphenol《Synergistic maximization of the carbohydrate output and lignin processability by combinatorial pretreatment》 was published in 2017. The authors were Liu, Zhi-Hua;Olson, Michelle L.;Shinde, Somnath;Wang, Xin;Hao, Naijia;Yoo, Chang Geun;Bhagia, Samarthya;Dunlap, John R.;Pu, Yunqiao;Kao, Katy C.;Ragauskas, Arthur J.;Jin, Mingjie;Yuan, Joshua S., and the article was included in《Green Chemistry》. The author mentioned the following in the article:

Lignocellulosic biorefineries have gained much attention worldwide as a potential solution to the challenges of energy demand and global climate change. However, the industrial implementation of biorefineries has been hindered by low fermentable sugar yields and low lignin processability. Combinatorial pretreatments with a low holding temperature were investigated in an effort to synergistically improve the carbohydrate output and lignin processability from corn stover. Upon combinatorial pretreatment with 1% H₂SO₄ for 30 min followed by 1% NaOH for 60 min at 120 °C, glucan and xylan conversion increased by 11.2% and 8.3% resp. relative to single pretreatment. This combinational pretreatment removed the amorphous portion, disrupted the rigid structure, and increased the water holding capacity of corn stover, thus increasing the hydrolysis performance. With whole fractionation by combinatorial pretreatment, glucose and xylose yields were 88.4% and 72.6%, resp., representing increases of 10.0% and 8.1%. The lignin yield was 19.7% in the solid residue and 77.6% in the liquid stream, which increased by 33.4%. When grown in fed-batch fermentation mode, a record level of polyhydroxyalkanoate (PHA) concentration (1.0 g l^-1) was obtained using lignin as a carbon source by Pseudomonas putida KT2440. Lignin characterization results showed that combinatorial pretreatment increased the G- and H-lignin content, reduced the β-β and β-O-4 groups, and fractionated more aromatic monomers, thus facilitating lignin processability into PHA. These results highlighted the use of combinational pretreatment at a low holding temperature as a means to synergistically maximize the carbohydrate output and lignin processability, which provides a unique set of features to improve the biorefining performance. The experimental procedure involved many compounds, such as 4-tert-Amylphenol (cas: 80-46-6) .

4-tert-acylphenol (cas:80-46-6) contains hydroxyl group. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble.Safety of 4-tert-Amylphenol

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application In Synthesis of 3,7-Dimethyloctan-3-ol《Iron-catalyzed borylation and silylation of unactivated tertiary, secondary, and primary alkyl chlorides》 was published in 2021. The authors were Wang, Siyu;Sun, Minghui;Zhang, Huan;Zhang, Juan;He, Yun;Feng, Zhang, and the article was included in《CCS Chemistry》. The author mentioned the following in the article:

Herein, we describe an iron-catalyzed borylation and silylation of unactivated alkyl chlorides, delivering the tertiary, secondary, and primary alkylboronic esters, and secondary, primary alkylsilanes with high efficiency. This protocol exhibits broad substrate scope and good functional group compatibility, allowing the efficient late-stage borylation of biorelevant compounds, thus offering an excellent platform in drug discovery and development. Preliminary mechanistic studies suggest that an alkyl radical was involved in this catalytic system. And 3,7-Dimethyloctan-3-ol (cas: 78-69-3) was used in the research process.

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Application In Synthesis of 3,7-Dimethyloctan-3-ol Metabolite observed in cancer metabolism. It has a role as a human metabolite.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Yingying;Qin, Hongmei;Wang, Mei;Li, Yuxiang;Sun, Daotong;Yang, Jianye published 《Research of synthesis and properties of benzthiadiazole-based non-covalent conformational locking small molecule》 in 2021. The article was appeared in 《Gongneng Cailiao》. They have made some progress in their research.Reference of 2-Hexyl-1-decanol The article mentions the following:

In recent years, fused-ring compounds have achieved remarkable results in the field of organic optoelectronic materials. In this paper, two novel benzothiadiazole (BT)-based conjugated non-covalently bonded ring small mol. compounds with the electron-absorbing groups fluorine and cyano group as ending-group, namely BT2T-IC and BT2T-IC4F, were synthesized successfully by Still coupling and Knoevengel condensation reaction, resp. On the one hand, SO and OH can be used to form non-covalent bond conformation lock in mols. to promote the planarity of mols. On the other hand, intramol. charge transfer can be enhanced by increasing the electron-lack of the end group. Under the synergistic action, the spectral absorption of the two new small mol. compounds is broadened to the near IR region, which is conducive to obtaining a wide spectral response. Their mol. structures were characterized by NMR, and their photophysics and electrochem. properties were investigated by d. functional theory (DFT) calculations, UV-vis absorption spectroscopy and cyclic voltammetry experiments The experimental procedure involved many compounds, such as 2-Hexyl-1-decanol (cas: 2425-77-6) .

2-Hexyl-1-decanol(cas: 2425-77-6) is a fatty acid that is found in the essential oils of plants and has been shown to have fungicidal properties.Reference of 2-Hexyl-1-decanol It has also been shown to inhibit the growth of Candida glabrata when used as a cationic surfactant.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application of 140-66-9《Identification of potential toxicants in sediments from an industrialized area in Pohang, South Korea: Application of a cell viability assay of microalgae using flow cytometry》 was published in 2021. The authors were An, Seong-Ah;Hong, Seongjin;Lee, Junghyun;Cha, Jihyun;Lee, Sunggyu;Moon, Hyo-Bang;Giesy, John P.;Khim, Jong Seong, and the article was included in《Journal of Hazardous Materials》. The author mentioned the following in the article:

Potential toxicants in sediments collected from an industrialized bay of Korea were identified by use of effect-directed anal. (EDA). Three marine microalgal bioassays (Dunaliella tertiolecta, Isochrysis galbana, and Phaeodactylum tricornutum) with diverse endpoints were employed. Initial screening of raw organic extracts of sediments indicated large variations among locations and species in a traditional endpoint “inhibition of growth”. After fractionation, inhibition of growths increased significantly, particularly in some fractions containing aromatics with log K_OW 5-6 (F2.6). While viabilities of cells were adversely affected in more fractions, including F2.6-F2.7 (log K_OW 5-7) and F3.5-F3.6 (log K_OW 4-6). Among the several endpoints of viability, esterase activity seemed to be more sensitive, followed by integrity of cell membranes, chlorophyll a, cell size, and intracellular complexity. Instrumental analyses indicated that toxicities to microalgae observed in F2.7 could not be fully explained by target PAHs. Full-scan screening anal. using GC-QTOFMS identified 58 compounds in F2.7 with matching scores ≥90%. Based on toxic potencies for these compounds predicted by ECOSAR, several causative agents, including 1-phenylpyrene, dibenz[a,c]anthracene, and picene were suggested. Overall, viability of microalgae provided sensitive and high-resolution toxicity screening of samples into integrative assessment of sediment.4-tert-Octylphenol (cas: 140-66-9) were involved in the experimental procedure.

4-tert-Octylphenol(cas: 140-66-9) is a common environmental pollutant showing weak estrogenic effects.Application of 140-66-9 It has been shown to cause harm to vertebrate male reproductive systems.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ai, Han-Jun;Zhang, Youcan;Zhao, Fengqian;Wu, Xiao-Feng published 《Rhodium-Catalyzed Carbonylative Synthesis of Aryl Salicylates from Unactivated Phenols》 in 2020. The article was appeared in 《Organic Letters》. They have made some progress in their research.SDS of cas: 599-64-4 The article mentions the following:

In the presence of RhCl₃ and 1,2-bis(dicyclohexylphosphino)ethane (dcpe), phenols underwent carbonylative esterification reactions with CO mediated by TEMPO in 1.4-dioxane/toluene to yield aryl salicylates such as Ph salicylate. Under similar conditions, but using 1,3-bis(diphenylphosphino)propane as the ligand, di-Ph carbonate was obtained as the major product. The mechanism of the reaction was studied using the reactions of potential intermediates and using kinetic isotope effects.4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) were involved in the experimental procedure.

4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.SDS of cas: 599-64-4 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts