Zhu, Lihui;Li, Jiasheng;Yang, Jun;Au-Yeung, Ho Yu published 《Cross dehydrogenative C-O coupling catalysed by a catenane-coordinated copper(I)》. The research results were published in《Chemical Science》 in 2020.Formula: C15H16O The article conveys some information:
Catalytic activity of copper(I) complexes supported by phenanthroline-containing catenane ligands towards a new C(sp3)-O dehydrogenative cross-coupling of phenols ROH (R = Ph, 4-(2-phenylpropan-2-yl)phenyl, 2-formyl-4-methoxyphenyl, etc.) and bromodicarbonyls R1C(O)CH(Br)C(O)R2 (R1 = Me, Ph, OBn, etc.; R2 = OEt, OMe, OtBu, OBn) is reported. As the phenanthrolines are interlocked by the strong and flexible mech. bond in the catenane, the active catalyst with an open copper coordination site can be revealed only transiently and the stable, coordinatively saturated Cu(I) pre-catalyst is quickly regenerated after substrate transformation. Compared with a control Cu(I) complex supported by non-interlocked phenanthrolines, the catenane-supported Cu(I) is highly efficient with a broad substrate scope, and can be applied in gram-scale transformations without a significant loss of the catalytic activity. This work demonstrates the advantages of the catenane ligands that provide a dynamic and responsive copper coordination sphere, highlighting the potential of the mech. bond as a design element in transition metal catalyst development. To complete the study, the researchers used 4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) .
4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.Formula: C15H16O 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.
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