Application In Synthesis of 3,7-Dimethyloctan-3-ol《Iron-catalyzed borylation and silylation of unactivated tertiary, secondary, and primary alkyl chlorides》 was published in 2021. The authors were Wang, Siyu;Sun, Minghui;Zhang, Huan;Zhang, Juan;He, Yun;Feng, Zhang, and the article was included in《CCS Chemistry》. The author mentioned the following in the article:
Herein, we describe an iron-catalyzed borylation and silylation of unactivated alkyl chlorides, delivering the tertiary, secondary, and primary alkylboronic esters, and secondary, primary alkylsilanes with high efficiency. This protocol exhibits broad substrate scope and good functional group compatibility, allowing the efficient late-stage borylation of biorelevant compounds, thus offering an excellent platform in drug discovery and development. Preliminary mechanistic studies suggest that an alkyl radical was involved in this catalytic system. And 3,7-Dimethyloctan-3-ol (cas: 78-69-3) was used in the research process.
3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Application In Synthesis of 3,7-Dimethyloctan-3-ol Metabolite observed in cancer metabolism. It has a role as a human metabolite.
Reference:
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