Sotto, Nicolas;Billamboz, Muriel;Chevrin-Villette, Carole;Len, Christophe published 《Selective Pinacol Coupling on Regeneratable Supported Acids in Sole Water》. The research results were published in《Journal of Organic Chemistry》 in 2015.Synthetic Route of C14H14O2 The article conveys some information:
Efficient pinacol coupling was developed in water, using a reusable heterogeneous supported acid source and zinc as cheap available metal source. This medium can be easily regenerated up to 10-fold without loss of activity. Moreover, supported acids enhance the selectivity of the pinacol coupling reaction compared with homogeneous acids. Thus, e.g., pinacol coupling of 4-bromobenzaldehyde in water using Zn as electron donor and Amberlyst 15 as proton source afforded 1,2-bis(4-bromophenyl)-1,2-ethanediol (82%,
rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas: 579-43-1 Synthetic Route of C14H14O2) has been used in the preparation of trans-methyl meso-hydrobenzoin phosphite.
Reference:
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