Doppler, Diandra team published research on Journal of Applied Crystallography in 2022 | 647-42-7

647-42-7, 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, also known as 1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol , is a useful research compound. Its molecular formula is C8H5F13O and its molecular weight is 364.1 g/mol. The purity is usually 95%.

1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol is a material used to improve nanotube composites. It is also used in the synthesis of a recyclable fluorous hydrazine carbothioate compound with NCS to catalyze the acetalization of aldehydes.

1H,1H,2H,2H-Tridecafluoro-1-n-octanol is a potent and selective halogenated hydrocarbon. It binds to DNA at the dinucleotide phosphate site, which is an important site for polymerase chain reaction (PCR) activation. 1HFN has been shown to be more effective than other halogenated hydrocarbons in vitro assays on rat liver microsomes. It has been used as an additive in wastewater treatment to remove organic contaminants and metal ions. In vivo studies have been carried out in CD-1 mice to determine the effects of 1HFN on the liver and kidneys; these studies showed no toxicological effects on these organs. 1HFN also has been shown to inhibit enzymes such as cytochrome P450 and monoamine oxidase B that are involved in drug metabolism and may lead to adverse reactions with drugs metabolized by these enzymes., Name: 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 647-42-7, formula is C8H5F13O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Name: 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol

Doppler, Diandra;Rabbani, Mohammad T.;Letrun, Romain;Cruz Villarreal, Jorvani;Kim, Dai Hyun;Gandhi, Sahir;Egatz-Gomez, Ana;Sonker, Mukul;Chen, Joe;Koua, Faisal H. M.;Yang, Jayhow;Youssef, Mohamed;Mazalova, Victoria;Bajt, Sasa;Shelby, Megan L.;Coleman, Matt A.;Wiedorn, Max O.;Knoska, Juraj;Schon, Silvan;Sato, Tokushi;Hunter, Mark S.;Hosseinizadeh, Ahmad;Kuptiz, Christopher;Nazari, Reza;Alvarez, Roberto C.;Karpos, Konstantinos;Zaare, Sahba;Dobson, Zachary;Discianno, Erin;Zhang, Shangji;Zook, James D.;Bielecki, Johan;de Wijn, Raphael;Round, Adam R.;Vagovic, Patrik;Kloos, Marco;Vakili, Mohammad;Ketawala, Gihan K.;Stander, Natasha E.;Olson, Tien L.;Morin, Katherine;Mondal, Jyotirmory;Nguyen, Jonathan;Meza-Aguilar, Jose Domingo;Kodis, Gerdenis;Vaiana, Sara;Martin-Garcia, Jose M.;Mariani, Valerio;Schwander, Peter;Schmidt, Marius;Messerschmidt, Marc;Ourmazd, Abbas;Zatsepin, Nadia;Weierstall, Uwe;Bruce, Barry D.;Mancuso, Adrian P.;Grant, Thomas;Barty, Anton;Chapman, Henry N.;Frank, Matthias;Fromme, Raimund;Spence, John C. H.;Botha, Sabine;Fromme, Petra;Kirian, Richard A.;Ros, Alexandra research published 《 Co-flow injection for serial crystallography at X-ray free-electron lasers》, the research content is summarized as follows. Serial femtosecond crystallog. (SFX) is a powerful technique that exploits X-ray free-electron lasers to determine the structure of macromols. at room temperature Despite the impressive exposition of structural details with this novel crystallog. approach, the methods currently available to introduce crystals into the path of the X-ray beam sometimes exhibit serious drawbacks. Samples requiring liquid injection of crystal slurries consume large quantities of crystals (at times up to a gram of protein per data set), may not be compatible with vacuum configurations on beamlines or provide a high background due to addnl. sheathing liquids present during the injection. Proposed and characterized here is the use of an immiscible inert oil phase to supplement the flow of sample in a hybrid microfluidic 3D-printed co-flow device. Co-flow generation is reported with sample and oil phases flowing in parallel, resulting in stable injection conditions for two different resin materials exptl. A numerical model is presented that adequately predicts these flow-rate conditions. The co-flow generating devices reduce crystal clogging effects, have the potential to conserve protein crystal samples up to 95% and will allow degradation-free light-induced time-resolved SFX.

647-42-7, 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, also known as 1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol , is a useful research compound. Its molecular formula is C8H5F13O and its molecular weight is 364.1 g/mol. The purity is usually 95%.

1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol is a material used to improve nanotube composites. It is also used in the synthesis of a recyclable fluorous hydrazine carbothioate compound with NCS to catalyze the acetalization of aldehydes.

1H,1H,2H,2H-Tridecafluoro-1-n-octanol is a potent and selective halogenated hydrocarbon. It binds to DNA at the dinucleotide phosphate site, which is an important site for polymerase chain reaction (PCR) activation. 1HFN has been shown to be more effective than other halogenated hydrocarbons in vitro assays on rat liver microsomes. It has been used as an additive in wastewater treatment to remove organic contaminants and metal ions. In vivo studies have been carried out in CD-1 mice to determine the effects of 1HFN on the liver and kidneys; these studies showed no toxicological effects on these organs. 1HFN also has been shown to inhibit enzymes such as cytochrome P450 and monoamine oxidase B that are involved in drug metabolism and may lead to adverse reactions with drugs metabolized by these enzymes., Name: 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts