With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 647-42-7, formula is C8H5F13O, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Category: alcohols-buliding-blocks
Dhamodharan, Duraisami;Ghoderao, Pradnya NP;Park, Cheol-Woong;Byun, Hun-Soo research published 《 Bubble and dew-point measurement of mixtures of 1H,1H,2H-perfluoro-1-octene and 1H,1H,2H,2H-perfluoro-1-octanol in supercritical CO2》, the research content is summarized as follows. In this article, solubility data are presented for the fluoro-monomer (meth)acrylate, which plays an important role as an organic solvent in several industrial processes. High-pressure phase equilibrium for 1H,1H,2H-perfluoro-1-octene + supercritical CO2 (PFOe + Sc-CO2), and 1H,1H,2H,2H-perfluoro-1-octanol + Sc-CO2 (PFOl + Sc-CO2) models were assessed in a static device at different temperatures starting from 313.2 to 393.2 K and maximum pressure of about 17.22 MPa. Temperature-pressure (T-p) diagrams of the PFOe + Sc-CO2 and PFOl + Sc-CO2 systems show mixture-critical curves between the critical temperatures of CO2 and PFOe or CO2 and PFOl. The solubility of PFOe and PFOl in the two systems gradually increases with increasing temperature at constant pressure. The exptl. curves for the PFOe + Sc-CO2 and PFOl + Sc-CO2 binary models show phase behavior of curve type-I. Correlations of exptl. results for the PFOe + Sc-CO2 and PFOl + Sc-CO2 models are compared with the P-R EOS using mixing rules with two parameters (κij, ηij). The root mean squared deviation (RMSD) percentages (%) for the two systems using the optimum factors evaluated at 353.2 K were 2.19% for PFOl + Sc-CO2 and 5.30% for PFOe + Sc-CO2. The RMSD (%) for the PFOl + Sc-CO2 model evaluated by the alterable factor at each temperature was 2.78%.
Category: alcohols-buliding-blocks, 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, also known as 1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol , is a useful research compound. Its molecular formula is C8H5F13O and its molecular weight is 364.1 g/mol. The purity is usually 95%.
1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol is a material used to improve nanotube composites. It is also used in the synthesis of a recyclable fluorous hydrazine carbothioate compound with NCS to catalyze the acetalization of aldehydes.
1H,1H,2H,2H-Tridecafluoro-1-n-octanol is a potent and selective halogenated hydrocarbon. It binds to DNA at the dinucleotide phosphate site, which is an important site for polymerase chain reaction (PCR) activation. 1HFN has been shown to be more effective than other halogenated hydrocarbons in vitro assays on rat liver microsomes. It has been used as an additive in wastewater treatment to remove organic contaminants and metal ions. In vivo studies have been carried out in CD-1 mice to determine the effects of 1HFN on the liver and kidneys; these studies showed no toxicological effects on these organs. 1HFN also has been shown to inhibit enzymes such as cytochrome P450 and monoamine oxidase B that are involved in drug metabolism and may lead to adverse reactions with drugs metabolized by these enzymes., 647-42-7.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts