With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 533-73-3, formula is C6H6O3, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Reference of 533-73-3
Dai, Mei;Luo, Zhiyong;Luo, Yiwen;Zheng, Qing;Zhang, Bingwen research published 《 Degradation of 2,6-dichlorophenol by ferrate (VI) oxidation: Kinetics, performance, and mechanism》, the research content is summarized as follows. The kinetics, performance and mechanism of the oxidative degradation of 2,6-dichlorophenol (2,6-DCP) by ferrate(VI) (Fe(VI)) were investigated in this study. The kinetics of oxidation of 2,6-DCP with Fe(VI) were studied as a function of pH (8.23-10.45) and temperature (20.0-33.5°C). The reaction follows a second-order rate law with first order in each reactant. The reaction rate constants were found to decrease non-linearly from 265.14 ± 14.10 M-1·s-1 at pH 8.23 to 9.80 ± 0.72 M-1·s-1 at pH 10.45. The individual species-specific second-order rate constants were calculated using pH dependence of species distributions of Fe(VI) (HFeO4– and FeO2-4) and 2,6-DCP (2,6-DCP and 2,6-DCP-). The reaction of deprotonated 2,6-DCP with protonated Fe(VI) was found to occur fastest among four parallel reactions between Fe(VI) and 2,6-DCP species. The correlation between temperature and rate constant showed that the activation energy of the reaction was 19.00 ± 1.82 kJ·mol-1. Removal performance depends on pH and molar ratio of Fe(VI) to 2,6-DCP. 2,6-DCP degradation efficiency decreased with increasing pH, which was in accord with pH dependence of the reaction constants Complete removal of 2,6-DCP by Fe(VI) was achieved at a 6:1 or higher molar ratio. The oxidized products (OPs) of 2,6-DCP were identified using high performance liquid chromatog. – mass spectrometry (HPLC-MS) and ion-selective electrode (ISE), and a dechlorination and ring-opening mechanism of 2,6-DCP degradation by Fe(VI) was proposed in detail. The results indicate that it is feasible and highly efficient for 2,6-DCP degraded by Fe(VI) to form nontoxic products.
Reference of 533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., 533-73-3.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts