Adeleye, Temitope Adewumi;Ajiboye, Clement Odunayo;Ojah, Emmanuel Onah;Okesanjo, Toyin Patrick;Moronkola, Dorcas Olufunke published 《Composition and antioxidant potential of leaf and stem essential oils from Nigerian Indigofera spicata Forssk》. The research results were published in《Journal of Medicinal Plants Research》 in 2021.Synthetic Route of C16H34O The article conveys some information:
The chem. compositions and antioxidant evaluation of the essential oils (EOs) obtained by hydrodistillation from the leaf and stem of Indigofera spicata Forssk (Fabaceae) grown in Nigeria have been studied. The EOs were analyzed using gas chromatog. coupled with mass spectrometry (GC-MS) and the antioxidant potential was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging ability method. The essential oils from the leaf and stem obtained in 0.007% and 0.009% yield have been found to contain 18 and 17 compounds resp. 13 compounds identified in the stem EOs make 90.2% of it. Sesquiterpenes (49.2%) and alcs. (30.7%) are dominant classes of compounds in the leaf EOs, with the most abundant compounds as caryophyllene (38.2%), humulene (6.2%) and m-eugenol (27.5%). Whereas esters (47.2%), and monoterpenoids (20.8%) dominate the stem essential oils with major constituents as linalyl acetate (23.9%), α-terpinyl acetate (12.8%), 3,5,5-trimethyhexyl acetate (9.4%), and linalool (20.8%). Common to both EOs were linalool, (leaf, 1.9%) caryophyllene (stem 5.9%), linanyl acetate (leaf, 2.5%). Comparison of the composition pattern of the leaf and stem EOs of I. spicata revealed significant qual. and quant. differences. Monoterpenes, sesquiterpenoid, diterpenoid, epoxide and ether were exclusive to the leaf oil while saturated, unsaturated hydrocarbons and anhydride were found only in the stem oil. The IC50 values of antioxidant evaluations show the leaf EO (36.97μg/mL) has more potential than the stem oil (39.89μg/mL) and comparable to that of the controls Vitamin C and Butylhydroxyl Anisole with IC50 values 24.20 and 24.21μg/mL resp. Most of these identified compounds have been known for various pharmacol. activities such as antioxidant, antitumor, anti-inflammatory, even as fragrances and the antioxidant potential of the oils justify the ethno-medicinal uses of I. spicata. The experimental procedure involved many compounds, such as 2-Hexyl-1-decanol (cas: 2425-77-6) .
2-Hexyl-1-decanol(cas: 2425-77-6) is a fatty acid that is found in the essential oils of plants and has been shown to have fungicidal properties.Synthetic Route of C16H34O It has also been shown to inhibit the growth of Candida glabrata when used as a cationic surfactant.
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