Serwa, Remigiusz;Nam, Tae-gyu;Valgimigli, Luca;Culbertson, Sean;Rector, Christopher L.;Jeong, Byeong-Seon;Pratt, Derek A.;Porter, Ned A. published 《Preparation and Investigation of Vitamin B6-Derived Aminopyridinol Antioxidants》. The research results were published in《Chemistry – A European Journal》 in 2010.HPLC of Formula: 148-51-6 The article conveys some information:
3-Pyridinols bearing amine substitution para to the hydroxylic moiety have previously been shown to inhibit lipid peroxidation more effectively than typical phenolic antioxidants, for example, α-tocopherol. We report here high-yielding, large-scale syntheses of mono- and bicyclic aminopyridinols from pyridoxine hydrochloride (i.e., vitamin B6). This approach provides straightforward, scaleable access to novel, potent, mol. scaffolds whose antioxidant properties have been investigated in homogeneous solutions and in liposomal vesicles. These mol. aggregates mimic cell membranes that are the targets of oxidative damage in vivo. To complete the study, the researchers used 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride (cas: 148-51-6) .
5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride(cas:148-51-6 HPLC of Formula: 148-51-6) is a strong antagonist of vitamin B6. Deoxypyridoxine hydrochloride has been used as an analytical reference standard for the quantification of the analyte in food samples using high performance liquid chromatography.
Reference:
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