Barnych, Bogdan team published research on European Journal of Medicinal Chemistry in 2020 | 7748-36-9

HPLC of Formula: 7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 7748-36-9, formula is C3H6O2, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. HPLC of Formula: 7748-36-9

Barnych, Bogdan;Singh, Nalin;Negrel, Sophie;Zhang, Yue;Magis, Damien;Roux, Capucine;Hua, Xiude;Ding, Zhewen;Morisseau, Christophe;Tantillo, Dean J.;Siegel, Justin B.;Hammock, Bruce D. research published 《 Development of potent inhibitors of the human microsomal epoxide hydrolase》, the research content is summarized as follows. Microsomal epoxide hydrolase (mEH) hydrolyzes a wide range of epoxide containing mols. Although involved in the metabolism of xenobiotics, recent studies associate mEH with the onset and development of certain disease conditions. This phenomenon is partially attributed to the significant role mEH plays in hydrolyzing endogenous lipid mediators, suggesting more complex and extensive physiol. functions. In order to obtain pharmacol. tools to further study the biol. and therapeutic potential of this enzyme target, we describe the development of highly potent 2-alkylthio acetamide inhibitors of the human mEH with IC50 values in the low nanomolar range. These are around 2 orders of magnitude more potent than previously obtained primary amine, amide and urea-based mEH inhibitors. Exptl. assay results and rationalization of binding through docking calculations of inhibitors to a mEH homol. model indicate that an amide connected to an alkyl side chain and a benzyl-thio function as key pharmacophore units.

HPLC of Formula: 7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts