In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Interception of amide ylides with sulfonamides: synthesis of (E)-N-sulfonyl amidines catalyzed by Zn(OTf)2, published in 2017, which mentions a compound: 7661-33-8, mainly applied to sulfonyl amidine preparation diastereoselective crystal structure mol; sulfonamide amide intermol condensation zinc catalyst, Reference of 1-(4-Chlorophenyl)pyrrolidin-2-one.
An efficient method was reported for the synthesis of (E)-N-sulfonyl amidines such as I [R1 = H, Me, Ph, etc.; R2 = Me, Ph, 2-thienyl, etc.; R3 = Me, i-Pr, Ph, etc.; R1R3 = (CH2)2, (CH2)3; R2R3 = (CH2)4, (CH2)5, (CH2)2O(CH2)2, etc.; R4 = Ph, 4-MeC6H4, 2-naphthyl, etc.] in good yields with excellent stereoselectivity via Zn-catalyzed intermol. condensation reaction between sulfonamides and various amides. The wide substrate scope, exceptional functional group tolerance, operational simplicity and neutral reaction conditions made this mechanistically novel method well suited for preparing amidine compounds I.
Although many compounds look similar to this compound(7661-33-8)Reference of 1-(4-Chlorophenyl)pyrrolidin-2-one, numerous studies have shown that this compound(SMILES:O=C1N(C2=CC=C(Cl)C=C2)CCC1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts