Lv, Xin; Bao, Weiliang published the article 《A β-Keto Ester as a Novel, Efficient, and Versatile Ligand for Copper(I)-Catalyzed C-N, C-O, and C-S Coupling Reactions》. Keywords: arylamide preparation copper catalyzed coupling keto ester ligand; arylimidazole preparation copper catalyzed coupling keto ester ligand; aryl ether preparation copper catalyzed coupling keto ester ligand; copper catalyzed coupling keto ester ligand aryl thioether preparation.They researched the compound: 1-(4-Chlorophenyl)pyrrolidin-2-one( cas:7661-33-8 ).Electric Literature of C10H10ClNO. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:7661-33-8) here.
Employing Et 2-oxocyclohexanecarboxylate as a novel, efficient, and versatile ligand, the copper-catalyzed coupling reactions of various N/O/S nucleophilic reagents with aryl halides could be successfully carried out under mild conditions. A variety of products including N-arylamides, N-arylimidazoles, aryl ethers, and aryl thioethers were synthesized in good to excellent yields.
Although many compounds look similar to this compound(7661-33-8)Electric Literature of C10H10ClNO, numerous studies have shown that this compound(SMILES:O=C1N(C2=CC=C(Cl)C=C2)CCC1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
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