What unique challenges do researchers face in 7661-33-8

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Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 7661-33-8, is researched, SMILESS is O=C1N(C2=CC=C(Cl)C=C2)CCC1, Molecular C10H10ClNOJournal, Suomen Kemistilehti B called Dipole moments of substituted 1-phenyl-2-pyrrolidones, Author is Virtanen, P. Olavi I.; Ruostesuo, Pirkko; Ruostesuo, Pirkko, the main research direction is dipole moment phenylpyrrolidones; phenylpyrrolidones dipole moment; pyrrolidones phenyl dipole moment; methylphenylpyrrolidones dipole moment; chlorophenylpyrrolidones dipole moment; methoxyphenylpyrrolidones dipole moment.Name: 1-(4-Chlorophenyl)pyrrolidin-2-one.

The dipole moments of 1-phenyl-2-pyrrolidone and its 2′-methyl, 3′-methyl, 4′-methyl, 2′-chloro, 3′-chloro, 4′-chloro, 2′-methoxy, 3′-methoxy, and 4′-methoxy derivatives were measured in dioxane at 30° and the dipole moments of the 1st 4 compounds also in cyclohexane at 30°. The dipole moments were larger in dioxane than in cyclohexane. The dipole moments of all the compounds except 1-(3-methoxyphenyl)-2-pyrrolidone and 1-(4-methoxyphenyl)-2-pyrrolidone agree with the values calculated by applying Eyring’s treatment and assuming free rotation of the pyrrolidonyl group about the bond joining it to the aromatic ring.

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