The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(4-Chlorophenyl)pyrrolidin-2-one(SMILESS: O=C1N(C2=CC=C(Cl)C=C2)CCC1,cas:7661-33-8) is researched.Product Details of 2208-59-5. The article 《Lactams. VIII. Conformation of N-aryl lactams》 in relation to this compound, is published in Tetrahedron. Let’s take a look at the latest research on this compound (cas:7661-33-8).
N-Aryl β-lactams were characterized by strong uv maximum at about 250 mμ. Some N-aryl γ-lactams also show similar absorption maximum but heavily substituted γ-lactams or N-phenyl δ-lactam display only low absorption in this region. A study of uv and N.M.R. spectra indicates that in N-aryl β-lactams, the heterocyclic ring and the three valences of N are planar and the N-aryl ring lies in the plane of the β-lactam. This planarity as well as the strong uv absorption are the result of an extended conjugation between the aryl ring and the amide function. Ortho substitution on the aryl ring causes a slight departure from this planarity and reduces the intensity of the uv absorption. In case of N-aryl γ-lactams, ortho substitution on the aryl ring causes enough departure from planarity to eliminate altogether the absorption maximum near 250 mμ. 22 references.
In addition to the literature in the link below, there is a lot of literature about this compound(1-(4-Chlorophenyl)pyrrolidin-2-one)Application of 7661-33-8, illustrating the importance and wide applicability of this compound(7661-33-8).
Reference:
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