So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Shook, Brian C.; Chakravarty, Devraj; Barbay, J. Kent; Wang, Aihua; Leonard, Kristi; Alford, Vernon; Powell, Mark T.; Rassnick, Stefanie; Scannevin, Robert H.; Carroll, Karen; Wallace, Nathaniel; Crooke, Jeffrey; Ault, Mark; Lampron, Lisa; Westover, Lori; Rhodes, Kenneth; Jackson, Paul F. researched the compound: Pyridine-3,5-dicarbonitrile( cas:1195-58-0 ).Recommanded Product: 1195-58-0.They published the article 《Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists》 about this compound( cas:1195-58-0 ) in Bioorganic & Medicinal Chemistry Letters. Keywords: thienopyrimidine preparation adenosine A2A antagonist. We’ll tell you more about this compound (cas:1195-58-0).
A novel series of benzyl substituted thieno[2,3-d]pyrimidines, e.g. I, were identified as potent A2A receptor antagonists. Several five- and six-membered heterocyclic replacements for the optimized methylfuran were explored. Select compounds effectively reverse catalepsy in mice when dosed orally.
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