So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Hartman, Tomas; Sturala, Jiri; Cibulka, Radek researched the compound: Pyridine-3,5-dicarbonitrile( cas:1195-58-0 ).Synthetic Route of C7H3N3.They published the article 《Two-Phase Oxidations with Aqueous Hydrogen Peroxide Catalyzed by Amphiphilic Pyridinium and Diazinium Salts》 about this compound( cas:1195-58-0 ) in Advanced Synthesis & Catalysis. Keywords: green chem oxidation amphiphilic pyridinium diazinium salt catalyst; oxidation aqueous hydrogen peroxide amphiphilic pyridinium diazinium salt catalyst. We’ll tell you more about this compound (cas:1195-58-0).
Amphiphilic pyridinium and diazinium salts were shown to be effective catalysts in two-phase (water/chloroform or water/dichloromethane) sulfoxidations and N-oxidations with hydrogen peroxide under mild conditions. This unprecedented oxidation method utilizes covalent bonding of hydrogen peroxide to a simple pyridinium or diazinium nucleus to increase the lipophilicity of the hydroperoxide species and to subsequently activate it for oxidations in a non-polar medium. The catalytic efficiency was found to depend on the type of heteroarenium core and on the lipophilicity of the catalyst. Five series of heteroarenium catalysts were prepared and investigated: 1-Alkyl-3,5-dicyanopyridinium, 1-alkyl-3,5-dinitropyridinium, 1-alkyl-3-cyanopyrazinium, 1-alkyl-4-cyanopyrimidinium and 1-alkyl-4-(trifluoromethyl)pyrimidinium triflates (alkyl=butyl, hexyl, octyl, decyl, dodecyl and hexadecyl). Among them, the 1-octyl-3,5-dinitropyridinium and 1-decyl-4-(trifluoromethyl)pyrimidinium triflates were found to be superior catalysts, showing the best stability and the highest catalytic activity, achieving acceleration by a factor of 350 relative to the non-catalyzed reaction. In contrast to other organocatalytic two-phase oxidations that use hydrogen peroxide, the presented method is characterized by high chemoselectivity and low catalyst loading (5 mol%) and with the reactions being performed under mild conditions, i.e., at 25° using diluted hydrogen peroxide and a non-basic aqueous phase. The catalysts have simple structures and are readily available from com. materials. Practical applications are demonstrated via the oxidation of several types of sulfides and amines.
I hope my short article helps more people learn about this compound(Pyridine-3,5-dicarbonitrile)Synthetic Route of C7H3N3. Apart from the compound(1195-58-0), you can read my other articles to know other related compounds.
Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts