Pratt, J. Richard; Massey, W. Dale; Pinkerton, Frank H.; Thames, Shelby F. published the article 《Organosilicon compounds. XX. Synthesis of aromatic diamines via trimethylsilyl-protecting aniline intermediates》. Keywords: protective group trimethylsilyl aniline; silyl trimethyl protective aniline; diamine aromatic; amine di aromatic; dinitrile lithioaniline; nitrile di lithioaniline; aniline lithio silyl keto; imine lithio; carbonyl compound diamino; keto di diamine; silicon diamine.They researched the compound: Pyridine-3,5-dicarbonitrile( cas:1195-58-0 ).Category: alcohols-buliding-blocks. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1195-58-0) here.
A synthetic approach utilizing a Me3Si protecting group was used to produce Si and diketo containing diamines. Thus, the halogen-metal interchange of N,N-bis(trimethylsilyl)bromoanilines with BuLi in ether produced Li derivatives, which were treated with dichloro silanes or dinitriles to afford the N,N-bis(trimethylsilyl)silicon containing dianilines or the corresponding lithioimines, resp. Hydrolysis removed the trimethylsilyl protecting groups and converted the lithioimines to the carbonyl compounds to afford the free diamines.
Here is just a brief introduction to this compound(1195-58-0)Category: alcohols-buliding-blocks, more information about the compound(Pyridine-3,5-dicarbonitrile) is in the article, you can click the link below.
Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts