The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(4-Chlorophenyl)pyrrolidin-2-one(SMILESS: O=C1N(C2=CC=C(Cl)C=C2)CCC1,cas:7661-33-8) is researched.Recommanded Product: 4385-62-0. The article 《Synthesis of haptens and potential radioligands and development of antibodies to insect growth regulators diflubenzuron and BAY SIR 8514》 in relation to this compound, is published in Journal of Agricultural and Food Chemistry. Let’s take a look at the latest research on this compound (cas:7661-33-8).
A variety of synthetic approaches were undertaken, leading to potential haptens and radioligands for the benzoylphenylurea insect growth regulators diflubenzuron [35367-38-5] and BAY SIR 8514 [64628-44-0]. One successful approach involved derivatization of the aniline N by Et 4-bromobutyrate followed by reaction with an appropriate isocyanate and cleavage of the Et ester to yield a free carboxypropyl “”handle””. Useful haptens were also synthesized by using a 3′-phenolic metabolite of diflubenzuron as well as acetate and amine functionalities in the 4′ position while the N-sulfenyl bond proved too unstable for use as an antigen. With the exception of the sulfenylated derivatives, the haptens lacked significant bol. activity on 3 insect species. Following protein coupling by the active ester or water-soluble diimide method, antibodies were raised to 2 diflubenzuron haptens in each of 7 rabbits immunized as demonstrated by radioimmunoassay using [14C]diflubenzuron, Ouchterlony gel diffusion, and immunoelectrophoresis.
From this literature《Synthesis of haptens and potential radioligands and development of antibodies to insect growth regulators diflubenzuron and BAY SIR 8514》,we know some information about this compound(7661-33-8)Safety of 1-(4-Chlorophenyl)pyrrolidin-2-one, but this is not all information, there are many literatures related to this compound(7661-33-8).
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