Decrypt The Mystery Of 651780-02-8

There is still a lot of research devoted to this compound(SMILES:CC(C)(C)OC(=O)N1N=CC2=CC(Br)=CC=C12)Reference of tert-Butyl 5-bromo-1H-indazole-1-carboxylate, and with the development of science, more effects of this compound(651780-02-8) can be discovered.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Journal of Organic Chemistry called Indazoles: Regioselective Protection and Subsequent Amine Coupling Reactions, Author is Slade, David J.; Pelz, Nicholas F.; Bodnar, Wanda; Lampe, John W.; Watson, Paul S., which mentions a compound: 651780-02-8, SMILESS is CC(C)(C)OC(=O)N1N=CC2=CC(Br)=CC=C12, Molecular C12H13BrN2O2, Reference of tert-Butyl 5-bromo-1H-indazole-1-carboxylate.

Indazoles are unselectively protected under strongly basic conditions to give a mixture at positions N-1 and N-2. Under mildly acidic conditions, regioselective protection at N-2 takes place. Thermodn. conditions lead to regioselective protection at N-1. This trend applies to various substituted indazoles. Protected 5-bromoindazoles participate in Buchwald reactions with a range of amines to generate novel derivatives

There is still a lot of research devoted to this compound(SMILES:CC(C)(C)OC(=O)N1N=CC2=CC(Br)=CC=C12)Reference of tert-Butyl 5-bromo-1H-indazole-1-carboxylate, and with the development of science, more effects of this compound(651780-02-8) can be discovered.

Reference:
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Alcohols – Chemistry LibreTexts