Chemistry Milestones Of 651780-02-8

There is still a lot of research devoted to this compound(SMILES：CC(C)(C)OC(=O)N1N=CC2=CC(Br)=CC=C12)Name: tert-Butyl 5-bromo-1H-indazole-1-carboxylate, and with the development of science, more effects of this compound(651780-02-8) can be discovered.

Name: tert-Butyl 5-bromo-1H-indazole-1-carboxylate. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: tert-Butyl 5-bromo-1H-indazole-1-carboxylate, is researched, Molecular C12H13BrN2O2, CAS is 651780-02-8, about Indazoles: Regioselective Protection and Subsequent Amine Coupling Reactions. Author is Slade, David J.; Pelz, Nicholas F.; Bodnar, Wanda; Lampe, John W.; Watson, Paul S..

Indazoles are unselectively protected under strongly basic conditions to give a mixture at positions N-1 and N-2. Under mildly acidic conditions, regioselective protection at N-2 takes place. Thermodn. conditions lead to regioselective protection at N-1. This trend applies to various substituted indazoles. Protected 5-bromoindazoles participate in Buchwald reactions with a range of amines to generate novel derivatives

There is still a lot of research devoted to this compound(SMILES：CC(C)(C)OC(=O)N1N=CC2=CC(Br)=CC=C12)Name: tert-Butyl 5-bromo-1H-indazole-1-carboxylate, and with the development of science, more effects of this compound(651780-02-8) can be discovered.

Reference:
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