Analyzing the synthesis route of 7661-33-8

As far as I know, this compound(7661-33-8)Safety of 1-(4-Chlorophenyl)pyrrolidin-2-one can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Scope and selectivity in palladium-catalyzed directed C-H bond halogenation reactions》. Authors are Kalyani, Dipannita; Dick, Allison R.; Anani, Waseem Q.; Sanford, Melanie S..The article about the compound:1-(4-Chlorophenyl)pyrrolidin-2-onecas:7661-33-8,SMILESS:O=C1N(C2=CC=C(Cl)C=C2)CCC1).Safety of 1-(4-Chlorophenyl)pyrrolidin-2-one. Through the article, more information about this compound (cas:7661-33-8) is conveyed.

Palladium-catalyzed ligand directed C-H activation/halogenation reactions have been extensively explored. Both the nature of the directing group and the substitution pattern on the arene ring of the substrate lead to different reactivity profiles, and often different and complementary products, in the presence and absence of the catalyst.

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Reference:
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