Adding a certain compound to certain chemical reactions, such as: 61266-36-2, Methyl 4-(3-hydroxyprop-1-yn-1-yl)benzoate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 61266-36-2, blongs to alcohols-buliding-blocks compound. SDS of cas: 61266-36-2
Compound 9 was prepared according to Scheme 7. [ Reaction of methyl 4-bromobenzoate (9. 1) with propargyl alcohol (9. 2) under Sonogashira conditions afforded compound 9. 3. Hydrogenation 9. 3 Obtaining compound 9. 4. Obtaining the acid after hydrolysis of the ester and subsequent treatment with acrylic acid under Dean and Stark conditions. The acid was reacted with intermediate 2 (3.6) to obtain diester 9. 7 and further reacted with diiodobenzene under Sonogashira conditions to obtain the target compound 9. 8
The synthetic route of 61266-36-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Merck Patent Gmbh / Merck patent Co.Ltd; Adlem, K; Parry, O. L; Skjonnemand, K; Wilkes, D; (51 pag.)CN103254083; (2016); B;,
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