Adding a certain compound to certain chemical reactions, such as: 59012-91-8, 4-(Hydroxymethyl)phenyl pivalate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 59012-91-8, blongs to alcohols-buliding-blocks compound. category: alcohols-buliding-blocks
[01561] A suspension of 2-methyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole (1 mmole) in thionyl chloride (5 mL) was warmed at reflux for 4 h. The cooled reaction mixture was evaporated to dryness and the resulting yellow residue was dissolved in methylene chloride and treated with a solution of the corresponding benzyl alcohol (4 mmole) and pyridine (2.5 mmole) in methylene chloride. After stirring at 25 C. for 24 h the reaction mixture was subjected to extraction and chromatography to give the titled compounds.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,59012-91-8, its application will become more common.
Reference:
Patent; Metabasis Therapeutics, Inc.; US6756360; (2004); B1;,
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