Introduction of a new synthetic route about (4-Butoxyphenyl)methanol

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 6214-45-5, (4-Butoxyphenyl)methanol, other downstream synthetic routes, hurry up and to see.

Related Products of 6214-45-5, Adding some certain compound to certain chemical reactions, such as: 6214-45-5, name is (4-Butoxyphenyl)methanol,molecular formula is C11H16O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6214-45-5.

Under nitrogen atmosphere, to a stirred mixture of commercially available (4-butoxyphenyl)-methanol (0.30 g, 1.66 mmol) in dry CH2C12 (8.0 mL), DMAP (0.020 g, 0.17 mmol) and 2-DPC (0.43 g, 1.99 mmol) were added. The reaction mixture was left at r.t. for 16 h, then diluted with CH2C12 (50 mL) and sequentially washed with sat. NH4C1 solution (50 mL), sat. NaHCO3 solution (3 x 50 mL) and brine (50 mL). The organic layer was dried over Na2504, filtered and concentrated to dryness to afford an oily product (0.423 g), as a mixture (1.7:1 ratio)of (4-butoxyphenyl)-methyl-2-pyridyl carbonate and (4-butoxyphenyl)-methyl-2-oxopyridine- 1- carboxylate. The mixture of isomers was not separated and used in the next step without any further purification. R = 2.61 mm; MS (ESI) m/z: 340 [M-K].

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 6214-45-5, (4-Butoxyphenyl)methanol, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA; PIOMELLI, Daniele; BANDIERA, Tiziano; BERTOZZI, Fabio; NUZZI, Andrea; FIASELLA, Annalisa; PONZANO, Stefano; PAGLIUCA, Chiara; REGGIANI, Angelo Mario; WO2014/144836; (2014); A2;,
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